Medicine

Accelerating ASO therapies from development to execution

.Completing passions.R.S., M.S., H.G. and also A.A.R. are actually coordinators of the 1M1M project. H.G. and A.A.R. are board of supervisors participants and R.S., M.S. and also A.A.R. are members of the scientific advising committee of N1C. A.A.R. makes known employment through LUMC, which possesses patents on exon-skipping modern technology, several of which has been accredited to BioMarin and also ultimately sublicensed to Sarepta. As co-inventor of several of these licenses, A.A.R. was actually qualified to a portion of nobilities. A.A.R. even further divulges serving as consultant for PTC Therapeutics, Sarepta Therapeutics, Regenxbio, Dyne Therapeutics, Lilly, BioMarin Pharmaceuticals Inc., Eisai, Entrada, Takeda, Splicesense, Galapagos, Sapreme, Italfarmaco as well as Astra Zeneca. In the past 5 years, A.A.R. additionally did impromptu seeking advice from for Alpha Anomeric. A.A.R. likewise mentions registration of the medical boards of advisers of Eisai, Hybridize Therapies, Silence Therapies, Sarepta Therapeutics, Sapreme as well as Mitorx. In the past 5 years, A.A.R. was additionally a scientific advisory board member for ProQR. Reimbursement for A.A.R. u00e2 s consulting and advising activities is spent to LUMC. Over the last 5 years, LUMC additionally obtained audio speaker honoraria coming from PTC Therapies, Alnylam Netherlands, Italfarmaco and Pfizer as well as cashing for contract research from Sapreme, Eisai, Galapagos, Synaffix as well as Alpha Anomeric. Venture financing is actually acquired coming from Sarepta Therapies and Entrada through unlimited gives. H.G. possesses nothing at all to make known relative to the subjects covered in this document. In the past 5 years, he has likewise obtained working as a consultant gratuity from UCB. M.S. received consultancy gratuity coming from Ionis, UCB, Prevail, Orphazyme, Biogen, Servier, Reata, GenOrph, AviadoBio, Biohaven, Zevra, Lilly and Solaxa over the last 5 years, all unconnected to the here and now manuscript. R.S. has absolutely nothing to reveal relative to the topics covered within this manuscript. She has acquired audio speaker and/or consultancy gratuity or even funding contributions from Abbvie, Bial, STADA and also Everpharma over the last 5 years.